Genetic variation in mother-child acute seroconverter pairs from Zambia

Ian wrote to us about:

Objective: To characterize the envelope (Env) glycoprotein of HIV-1 in mother-infant pairs (MIP) that underwent near simultaneous or acute-phase seroconversion, we examined the Env sequence of the transmitted viruses and compare viral evolution within the pair. Design: Three MIP from a Zambian cohort that seroconverted at the same sampling time were identified and followed longitudinally. Methods: The V1-V5 region of the HIV-1 Env gene was sequenced for each sample collected. Phylogenetic and population…(read more)

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April 22, 2008 | Filed Under AIDS

 

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